Therapeutic Solutions International, Inc. manufacture and sell (directly and through distributors and sublicensees), in non-United States countries, plastic intraoral devices known as Anterior Midpoint Stop Appliances (AMPSA Products). The AMPSA Products are used for the treatment and prevention of common neurological and temporomandibular disorders including migraine headaches, migraine pain and bruxism. It sells its AMPSA Products under its registered trademarks AMPSA CS and Migran-X, and under the legacy in-licensed trademarks NTI and NTI-tss . The Company also provides AMPSA-related educational programs. AMPSA Products include a patented design that the Company refers to as the discluding element. This discluding element prevents the posterior and canine teeth from clenching, thereby preventing the triggering pathology leading to many migraine headaches from occurring.